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GermanyCOVID-19Europe

COVID-19 in Germany

Germany was home to BioNTech, the company that developed the world's first authorized COVID-19 mRNA vaccine — while also battling 170,000+ deaths domestically.

VirusWatch Editorial Team — Last reviewed: May 2025
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Key Data

MetricData
Total confirmed cases~38 million
Official deaths>170,000
Vaccine contributionBioNTech (Mainz) — Pfizer-BioNTech mRNA vaccine
Healthcare systemAmong highest ICU beds per capita in Europe
Federal structure16 states (Länder) with state-level public health authority
Health authorityRobert Koch-Institut (RKI), Berlin

BioNTech: Germany's Vaccine Contribution

The world's first authorized COVID-19 vaccine was developed not by a large pharmaceutical company, but by a small oncology startup in Mainz, Germany. BioNTech was founded in 2008 by Uğur Şahin (an oncologist of Turkish origin who immigrated to Germany as a child) and Özlem Türeci. Their company had been developing mRNA-based cancer immunotherapies when the SARS-CoV-2 sequence was published in January 2020. Şahin read a paper about the outbreak during a family wedding and immediately pivoted BioNTech's platform to the coronavirus. In partnership with Pfizer for manufacturing and distribution, the Pfizer-BioNTech vaccine was authorized by the UK on December 2, 2020, and began global distribution. Germany also hosts CureVac, another mRNA biotech that developed a COVID vaccine (though with lower efficacy in trials).

Germany's Pandemic Response

Germany's initial response in spring 2020 was relatively effective — Chancellor Merkel (a quantum chemist by training) communicated clearly about exponential growth, and Germany's high ICU bed capacity allowed it to accept patients from overwhelmed Italian and French hospitals. Germany had more ICU beds per capita than almost any other European country (~30 per 100,000). However, Germany struggled in subsequent waves. The winter 2021 wave (before widespread vaccination) was Germany's most deadly period, with daily deaths exceeding 500 and some ICUs in Bavaria and Saxony reaching capacity. Vaccination uptake was slower than expected, with eastern German states showing particularly low coverage.

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FAQ

BioNTech was founded by Uğur Şahin and Özlem Türeci in Mainz, Germany in 2008. Şahin pivoted the company's mRNA cancer immunotherapy platform to SARS-CoV-2 in January 2020 after reading about the emerging outbreak. BioNTech partnered with Pfizer for manufacturing, clinical trials, and global distribution. The vaccine was the first COVID-19 vaccine authorized anywhere in the world (UK, December 2, 2020).

Eastern German states (Saxony, Thuringia, Brandenburg) had significantly lower COVID vaccination rates than western Germany. Analysts point to higher distrust of government institutions (a legacy of GDR experience), stronger AfD (far-right party) presence, and higher rates of COVID skepticism. Saxony had Germany's lowest vaccination rate and highest COVID death rate per capita in late 2021.

Sources: Robert Koch-Institut (RKI) COVID reports; BioNTech corporate history; ECDC Germany COVID data; Destatis excess mortality Germany.

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